- Exploring Sustainable CO2 Utilization in E. coli, 2025-2028, Funded by TUBITAK 2515-COST (Project No. 225M432), Role: Principal Investigator.
- Identification of metabolic pathways associated with efficient utilization of C1 substrates in Escherichia coli, 2025-2027, Funded by Boğaziçi University Research Fund (Project No. 20481), Role: Principal Investigator.
- Investigation of the Interaction Between Epithelial-Mesenchymal Transition and Ferroptosis in Triple-Negative Breast Cancer and Evaluation of Its Use for Novel Treatment Combinations, 2025-2028, Funded by TUBITAK ARDEB 1001 (Project No. 125Z414), Role: Researcher. (PI: Özlem Ulucan Açan)
- Characterization of hybrid epithelial-mesenchymal transition states in cancer cells and identification of drug candidates that target these hybrid states, 2022-2026, Funded by TUBITAK ARDEB 3501 (Project No. 121Z680), Role: Researcher. (PI: Özlem Ulucan Açan)
- MODY (Maturity-onset of Diabetes of Youth) Pathogenesis: The Role of the c-MYC Transcription Factor, 2023-2025, Funded by TUSEB (Project No. 28946), Role: Researcher. (PI: Özlem Yalçın Çapan)
- Investigation of the effectiveness of CO2 fixation pathways through thermodynamic feasibility analysis of E. coli metabolic model under dynamic conditions, 2021-2024, Funded by TUBITAK ARDEB 1001 (Project No. 221M108), Role: Principal Investigator.
- Development of Escherihia coli kinetic model for sustainable production from renewable resources, 2021-2023, Funded by Istanbul Bilgi University Research Fund, Role: Principal Investigator.
- Analysis of the common effects of doxorubicin on different disease types by integrative genome-wide approaches, 2019-2021, Funded by Istanbul Bilgi University Research Fund, Role: Principal Investigator.
- Investigation of intracellular effects of chemotherapeutic drugs using systems biology approaches and genome-wide models, 2014-2016, Funded by TUBITAK BIDEB 2232 (Project No. 114C062), Role: Principal Investigator.
- Computational modeling approaches and fluxomics, 2010-2012, Funded by NCSB (Netherlands Consortium for Systems Biology) - NBIC (Netherlands Bioinformatics Centre), Role: Postdoctoral Researcher.
Title
Assoc. Prof. Hilal Taymaz Nikerel
Email Address
hilal.taymaz![[at]](/sites/default/files/at.png)
boun.edu.tr
boun.edu.trPhone Number
0 212 359 7471
About
Our research focuses on understanding the function and intracellular regulation of complex biochemical processes and designing these systems in the long term using systems biology approaches. In this context, our work requires the use of biochemical engineering tools that require both computational and experimental techniques.
Our ongoing research projects investigate the contribution of Escherichia coli to CO2 fixation through thermodynamic feasibility analysis, kinetic model development, and transcriptomic data analysis. This reveals the potential of these systems in the production of platform chemicals, enables us to propose strategies for improving microbial production processes, and contributes to the development of alternative technologies to reduce carbon emissions and mitigate the effects of climate change.
